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Livres
Articles (54)
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T-cell clonality in immune responses

Mala K Maini, Giulia Casorati, Paolo Dellabona, Andreas Wack, Peter C.L Beverley

Journal:

Immunology Today

Année:

1999

Langue:

english

Fichier:

PDF, 167 KB

english, 1999

CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

Matthew Hoare, William T.H. Gelson, Abhi Das, Jean M. Fletcher, Susan E. Davies, Martin D. Curran, Sarah L. Vowler, Mala K. Maini, Arne N. Akbar, Graeme J.M. Alexander

Journal:

Journal of Hepatology

Année:

2010

Langue:

english

Fichier:

PDF, 941 KB

english, 2010

Liver sampling: a vital window into HBV pathogenesis on the path to functional cure

Gill, Upkar S, Pallett, Laura J, Kennedy, Patrick T F, Maini, Mala K

Journal:

Gut

Année:

2018

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2018

Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection

Peppa, Dimitra, Pedroza-Pacheco, Isabela, Pellegrino, Pierre, Williams, Ian, Maini, Mala K., Borrow, Persephone

Journal:

Frontiers in Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2018

Restoring, releasing or replacing adaptive immunity in chronic hepatitis B

Maini, Mala K., Burton, Alice R.

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Année:

2019

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2019

T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection

Mala K. Maini, Stephanie Reignat, Carolina Boni, Graham S. Ogg, Abigail S. King, Fabio Malacarne, George J. M. Webster, Antonio Bertoletti

Journal:

European Journal of Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 257 KB

english, 2000

The influence of T cell cross-reactivity on HCV-peptide specific human T cell response

Patrick T.F. Kennedy, Simonetta Urbani, Rebecca A. Moses, Barbara Amadei, Paola Fisicaro, Jilly Lloyd, Mala K. Maini, Geoffrey Dusheiko, Carlo Ferrari, Antonio Bertoletti

Journal:

Hepatology

Année:

2006

Langue:

english

Fichier:

PDF, 766 KB

english, 2006

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

Anna Schurich, Pooja Khanna, A. Ross Lopes, Ki Jun Han, Dimitra Peppa, Lorenzo Micco, Gaia Nebbia, Patrick T.F. Kennedy, Anna-Maria Geretti, Geoffrey Dusheiko, Mala K. Maini

Journal:

Hepatology

Année:

2011

Langue:

english

Fichier:

PDF, 1007 KB

english, 2011

Impaired innate immune responses in patients with chronic HBV infection

Dimitra Peppa, Claire Dunn, Celeste Pallant, Abhishek Das, Gidon Ellis, Richard Gilson, Mala Maini

Journal:

Journal of Infection

Année:

2008

Langue:

english

Fichier:

PDF, 54 KB

english, 2008

Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?

Antonio Bertoletti, Mala K Maini

Journal:

Current Opinion in Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 238 KB

english, 2000

Living in the liver: hepatic infections

Protzer, Ulrike, Maini, Mala K., Knolle, Percy A.

Journal:

Nature Reviews Immunology

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

Incubation Phase of Acute Hepatitis B in Man: Dynamic of Cellular Immune Mechanisms

George J.M. Webster, Stephanie Reignat, Mala K. Maini, Simon A. Whalley, Graham S. Ogg, Abigail King, David Brown, Peter L. Amlot, Roger Williams, Diego Vergani, Geoffrey M. Dusheiko, Antonio Bertolet

Journal:

Hepatology

Année:

2000

Langue:

english

Fichier:

PDF, 536 KB

english, 2000

The molecular basis of the failed immune response in chronic HBV: Therapeutic implications

Mala K. Maini, Anna Schurich

Journal:

Journal of Hepatology

Année:

2010

Langue:

english

Fichier:

PDF, 540 KB

english, 2010

Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines

Adam J. Gehring, Shao-An Xue, Zi Zong Ho, Denise Teoh, Christiane Ruedl, Adeline Chia, Sarene Koh, Seng Gee Lim, Mala K. Maini, Hans Stauss, Antonio Bertoletti

Journal:

Journal of Hepatology

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?

Antonio Bertoletti, Mala K Maini

Journal:

Current Opinion in Microbiology

Année:

2000

Langue:

english

Fichier:

PDF, 318 KB

english, 2000

Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

Mala K. Maini, Carolina Boni, Graham S. Ogg, Abigail S. King, Stephanie Reignat, Chun Kyon Lee, Juan R. Larrubia, George J.M. Webster, Andrew J. McMichael, Carlo Ferrari, Roger Williams, Diego Vergani

Journal:

Gastroenterology

Année:

1999

Langue:

english

Fichier:

PDF, 583 KB

english, 1999

Obituary

Gill, Upkar S., Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D., Foster, Graham, Maini, Mala, Kennedy, Patrick T.

Journal:

The Lancet

Année:

1942

Langue:

english

Fichier:

PDF, 449 KB

english, 1942

Sa1313 Sequential Nuc Therapy Following Pegylated Interferon-Alpha Exposure Restores Innate Immune Responses Conferring a Treatment Advantage Over Nuc Monotherapy in Chronic Hepatitis B

Gill, Upkar S., Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D., Foster, Graham, Maini, Mala, Kennedy, Patrick T.

Journal:

Gastroenterology

Année:

2014

Langue:

english

Fichier:

PDF, 176 KB

english, 2014

Mo1837 Maximal Boosting of Innate Immunity During Pegylated Interferon-Aplha Therapy is Reached at 48 Weeks in E-Antigen Positive Chronic Hepatitis B

Gill, Upkar, Papadaki, Maria, Peppa, Dimitra, Micco, Lorenzo, Li, Li, Ushiro-Lumb, Ines, Foster, Graham, Maini, Mala, Kennedy, Patrick T.

Journal:

Gastroenterology

Année:

2012

Langue:

english

Fichier:

PDF, 82 KB

english, 2012

Direct-acting antivirals trump interferon-alpha in their capacity to rescue exhausted T cells upon HCV clearance

Maini, Mala K., Schurich, Anna

Journal:

Journal of Hepatology

Année:

2014

Langue:

english

Fichier:

PDF, 368 KB

english, 2014

Effect of HIV Infection and Antiretroviral Therapy on Hepatitis B Virus (HBV)–Specific T Cell Responses in Patients Who Have Resolved HBV Infection

Lascar, R. Monica, Lopes, A. Ross, Gilson, Richard J., Dunn, Claire, Johnstone, Ruth, Copas, Andrew, Reignat, Stephanie, Webster, George, Bertoletti, Antonio, Maini, Mala K.

Journal:

The Journal of Infectious Diseases

Année:

2005

Langue:

english

Fichier:

PDF, 765 KB

english, 2005

Reconstitution of Hepatitis B Virus (HBV)–Specific T Cell Responses with Treatment of Human Immunodeficiency Virus/HBV Coinfection

Lascar, R. Monica, Gilson, Richard J., Lopes, A. Ross, Bertoletti, Antonio, Maini, Mala K.

Journal:

The Journal of Infectious Diseases

Année:

2003

Langue:

english

Fichier:

PDF, 167 KB

english, 2003

Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections

Davidson, Sophia, Maini, Mala K., Wack, Andreas

Journal:

Journal of Interferon & Cytokine Research

Année:

2015

Langue:

english

Fichier:

PDF, 770 KB

english, 2015

Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study

Arenas-Pinto, Alejandro, Milinkovic, Ana, Peppa, Dimitra, McKendry, Anna, Maini, Mala, Gilson, Richard

Journal:

BMC Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 334 KB

english, 2015

T cell receptor-therapy in HBV-related hepatocellularcarcinoma

Bertoletti, Antonio, Brunetto, Maurizia, Maini, Mala K, Bonino, Ferruccio, Qasim, Waseem, Stauss, Hans

Journal:

OncoImmunology

Année:

2015

Langue:

english

Fichier:

PDF, 177 KB

english, 2015

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection

Peppa, Dimitra, Micco, Lorenzo, Javaid, Alia, Kennedy, Patrick T. F., Schurich, Anna, Dunn, Claire, Pallant, Celeste, Ellis, Gidon, Khanna, Pooja, Dusheiko, Geoffrey, Gilson, Richard J., Maini, Mala K

Journal:

PLoS Pathogens

Année:

2010

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2010

The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells

Schurich, Anna, Pallett, Laura J., Lubowiecki, Marcin, Singh, Harsimran D., Gill, Upkar S., Kennedy, Patrick T., Nastouli, Eleni, Tanwar, Sudeep, Rosenberg, William, Maini, Mala K., Walker, Christophe

Journal:

PLoS Pathogens

Année:

2013

Langue:

english

Fichier:

PDF, 953 KB

english, 2013

Optimal Management of Hepatitis B Virus Infection – EASL Special Conference

Lampertico, Pietro, Maini, Mala, Papatheodoridis, George

Journal:

Journal of Hepatology

Année:

2015

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2015

Reply to: “To target or not to target viral antigens in HBV related HCC?”

Qasim, Waseem, Brunetto, Maurizia, Gehring, Adam J., Maini, Mala K., Bonino, Ferruccio, Stauss, Hans, Bertoletti, Antonio

Journal:

Journal of Hepatology

Année:

2015

Langue:

english

Fichier:

PDF, 368 KB

english, 2015

Innate and Adaptive Immune Responses in Hepatitis B Virus Infection

Das, Abhishek, Maini, Mala K.

Journal:

Digestive Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 209 KB

english, 2010

Pathogenesis of hepatitis B virus infection and potential for new therapies

Peppa, Dimitra, Maini, Mala K

Journal:

British Journal of Hospital Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 236 KB

english, 2012

The role of innate immunity in the immunopathology and treatment of HBV infection

Maini, Mala K., Gehring, Adam J.

Journal:

Journal of Hepatology

Année:

2016

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2016

Immunological Memory || Differences in the Regulation of CD4 and CD8 T-Cell Clones during Immune Responses

Peter C. L. Beverley and Mala K. Maini

Journal:

Philosophical Transactions Biological Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2000

HBV in 2016: Global and immunotherapeutic insights into hepatitis B

Maini, Mala K., Bertoletti, Antonio

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Année:

2017

Langue:

english

Fichier:

PDF, 250 KB

english, 2017

Effect of in-vivo hepatitis B viral load suppression after interferon exposure on natural killer and T-cell responsiveness

Gill, Upkar S, Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D, Le Bert, Nina, Rivino, Laura, Kunasegaran, Kamini, Tan, Damien, Bertoletti, Antonio, Maini, Mala K, Kennedy, Patrick T F

Journal:

The Lancet

Année:

2017

Langue:

english

Fichier:

PDF, 54 KB

english, 2017

Natural Killer Cells in Liver Disease

Male, Victoria, Stegmann, Kerstin, Easom, Nicholas, Maini, Mala

Journal:

Seminars in Liver Disease

Année:

2017

Langue:

english

Fichier:

PDF, 286 KB

english, 2017

Defective T-cell immunity in hepatitis B virus infection: why therapeutic vaccination needs a helping hand

Maini, Mala K, Pallett, Laura J

Journal:

The Lancet Gastroenterology & Hepatology

Année:

2018

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2018

IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction

Easom, Nicholas J. W., Stegmann, Kerstin A., Swadling, Leo, Pallett, Laura J., Burton, Alice R., Odera, Dennis, Schmidt, Nathalie, Huang, Wei-Chen, Fusai, Giuseppe, Davidson, Brian, Maini, Mala K.

Journal:

Frontiers in Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 7.13 MB

english, 2018

NK Cells: A Double-Edged Sword in Chronic Hepatitis B Virus Infection

Maini, Mala K., Peppa, Dimitra

Journal:

Frontiers in Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 901 KB

english, 2013

Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda

Laing, Nicolas, Tufton, Henry, Ochola, Emmanuel, P’Kingston, Ojok Godfrey, Maini, Mala K, Easom, Nicholas

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Année:

2018

Langue:

english

Fichier:

PDF, 392 KB

english, 2018

Fine needle aspirates comprehensively sample intrahepatic immunity

Gill, Upkar S, Pallett, Laura J, Thomas, Niclas, Burton, Alice R, Patel, Amit A, Yona, Simon, Kennedy, Patrick T F, Maini, Mala K

Journal:

Gut

Année:

2018

Langue:

english

Fichier:

PDF, 4.27 MB

english, 2018

Spatio-temporal differences in presentation of CD8 T cell epitopes during HBV infection.

Khakpoor, Atefeh, Ni, Yi, Chen, Antony, Ho, Zi Zong, Oei, Vincent, Yang, Ninghan, Giri, Reshmi, Chow, Jia Xin, Tan, Anthony T., Kennedy, Patrick T., Maini, Mala, Urban, Stephan, Bertoletti, Antonio

Journal:

Journal of Virology

Année:

2018

Langue:

english

Fichier:

PDF, 5.40 MB

english, 2018

CD8+ T cells cure without killing

Maini, Mala K.

Journal:

Nature Reviews Immunology

Année:

2019

Langue:

english

Fichier:

PDF, 421 KB

english, 2019

Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response

Schwenzer, Hagen, Jühling, Frank, Chu, Alexander, Pallett, Laura J., Baumert, Thomas F., Maini, Mala, Fassati, Ariberto

Journal:

Cell Reports

Année:

2019

Langue:

english

Fichier:

PDF, 4.85 MB

english, 2019

FRI-162-Prime-boost vaccination strategies using chimpanzee-adeno and MVA viral vectored vaccines encoding multiple HBV antigens (CPmutS) and class II invariant chain molecular adjuvants induces robust T-cell and anti-HBs antibody response in mice

Cargill, Tamsin, Donnison, Timothy, Ansari, Azim, Maini, Mala, Evans, Tom, Barnes, Eleanor, Chinnakannan, Senthil Kumar

Journal:

Journal of Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 501 KB

english, 2019

FRI-143-Liver-resident HBV-specific CD8+ T cells are long-lived and can be replenished by allogenic responses following transplantation

Pallett, Laura J, Burton, Alice, Amin, Oliver E, Zakeri, Nekisa, Thorburn, Douglas, Yona, Simon, Maini, Mala

Journal:

Journal of Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 163 KB

english, 2019

FRI-132-In vitro modulation by TLR8 agonist GS-9688 of multiple regulatory cell types in patients with chronic hepatitis B

Amin, Oliver E, Colbeck, Emily, Daffis, Stephane, Pattabiraman, Divya, Sitali, Colette, Rosenberg, William, Fletcher, Simon, Maini, Mala, Pallett, Laura J

Journal:

Journal of Hepatology

Année:

2019

Fichier:

PDF, 60 KB

2019

Liver-resident CD8+ T cells: learning lessons from the local experts

Swadling, Leo, Pallett, Laura J., Maini, Mala K.

Journal:

Journal of Hepatology

Année:

2020

Fichier:

PDF, 380 KB

2020

Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy

PerpiÃ±Ã¡n, Elena, PÃ©rez-Del-Pulgar, SofÃa, LondoÃ±o, MarÃa-Carlota, MariÃ±o, Zoe, Bartres, ConcepciÃ³n, GonzÃ¡lez, Patricia, GarcÃa-LÃ³pez, Mireia, Pose, Elisa, Lens, Sabela, Maini, Mala K., Forn

Journal:

Frontiers in Immunology

Année:

2020

Langue:

english

Fichier:

PDF, 7.52 MB

english, 2020

The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV

Chinnakannan, Senthil K., Cargill, Tamsin N., Donnison, Timothy A., Ansari, M. Azim, Sebastian, Sarah, Lee, Lian Ni, Hutchings, Claire, Klenerman, Paul, Maini, Mala K., Evans, Tom, Barnes, Eleanor

Journal:

Vaccines

Année:

2020

Fichier:

PDF, 4.55 MB

2020